The IEA's 2023 update emphasizes the importance of carbon capture technologies, efficient space cooling equipment, and clean energy transitions in achieving net zero emissions by 2050. Metal-organic frameworks (MOFs) are identified as key players in accelerating industrial decarbonization. MOFs offer diverse applications such as carbon capture solutions for hard-to-abate industries, reducing the carbon footprint in chemical production, addressing lithium supply challenges, widening the scope of refrigerant reclamation, and enhancing energy efficiency in HVAC systems. 1. MOF sorbents for point source carbon capture solutions: MOFs act as selective filters that adsorb CO2 effectively, with regeneration pathways that offer energy efficiency compared to conventional methods. 2. Carbon footprint reduction in chemical production: MOFs can revolutionize separation technologies, exemplified by UniSieve's membrane technology cutting energy consumption in propylene separation. 3. Direct lithium extraction technologies: MOFs enable selective lithium extraction, crucial for meeting the soaring demand in clean energy technologies, with companies like EnergyX leading the way in developing sustainable lithium supply chains. 4. Refrigerant reclamation: MOFs facilitate the separation of refrigerants, aiding in reducing the environmental impact of fluorocarbon refrigerants and aligning with emission reduction targets. 5. Energy-efficient HVAC systems: MOF-coated technologies like AirJoule® offer a sustainable approach to space cooling, reducing electricity consumption significantly and attracting partnerships for commercialization. While MOFs hold immense potential for industrial decarbonization, challenges exist in their widespread adoption. IDTechEx's report reflects on the role of MOFs in driving next-generation technologies, highlighting their significance in the global shift towards sustainable practices and climate action.