The study focuses on the optimization of hydrogen production from biogas as a sustainable solution to reduce greenhouse gas emissions and replace fossil fuels. By utilizing the DWSIM chemical process simulator and response surface methodology, researchers aimed to improve the efficiency of the conversion process. Through modeling and validation, key process parameters such as biogas and steam flow rates, reactor temperature, and pressure were analyzed. Sensitivity analysis highlighted the significant impact of these parameters on hydrogen yield, with pressure showing the least influence. Furthermore, the study employed Design Expert software to optimize the hydrogen production process using Central composite design. By considering biogas flow rate, steam flow rate, inlet temperature, and reformer reactor pressure as input parameters, researchers identified optimal conditions that resulted in a substantial increase in hydrogen yield. The model and parameters were statistically significant, with pressure having the least effect on yield. The study's findings indicated that with a biogas flow rate of 57 kg/hr, steam flow rate of 33.97 kg/hr, inlet temperature of 954.38 °C, and pressure of 12.52 bar, a maximum hydrogen yield of 65.992% was achieved. Validation through simulation tools yielded a hydrogen yield of 64.874% with minimal error margin, demonstrating the effectiveness of the optimized parameters. Overall, this research contributes to the field of sustainable energy by providing insights into the optimization of hydrogen production from biogas. The study underscores the importance of process optimization in enhancing hydrogen yield and presents a viable alternative to traditional fossil fuels, thereby addressing key sustainability challenges.