The article highlights the importance of green hydrogen (H2) in reducing carbon emissions in bio-refineries, focusing on the production of 1,3-PDO. It discusses the significance of different types of hydrogen (grey, blue, green) in industrial applications and their varying carbon footprints. The study presents a comparative case analysis showing that using green H2 can lead to a significant reduction in carbon emissions in bio-product processing, potentially achieving a net negative carbon footprint for bio-commodities. The article also addresses the challenges facing the production of 1,3-PDO, emphasizing the need for more sustainable and efficient methods. Various synthetic routes for 1,3-PDO production are discussed, including biological conversion of glycerol and direct hydrogenolysis methods. The research aims to evaluate the energy consumption, CO2 emissions, and environmental impacts associated with H2 utilization in bio-refining processes. By conducting detailed simulations and analysis, the study seeks to establish a reliable methodology for assessing the role of H2 sources in the overall carbon footprint of bio-commodity products. Overall, the article emphasizes the positive impact of green hydrogen in achieving sustainability goals in industrial processes.