The study published in Science Advances delves into the complex phenomenon of hydrogen embrittlement, a longstanding challenge in materials science. Led by Dr. Mengying Liu from Washington and Lee University in collaboration with experts at Texas A&M University, the research focuses on crack formation in a robust nickel-base alloy, Inconel 725, recognized for its strength and corrosion resistance. By investigating crack initiation in flawless alloy samples in real-time, the team challenges the prevailing HELP hypothesis, demonstrating that crack initiation does not align with areas of high localized plasticity. This groundbreaking approach, led by Dr. Michael J. Demkowicz, offers new insights into the mechanisms of hydrogen embrittlement. Understanding crack initiation dynamics is essential, as post-crack examination cannot capture the crucial hydrogen-metal interactions due to hydrogen escape. The study's implications extend beyond academic curiosity, as predicting hydrogen embrittlement is essential for safeguarding future infrastructure in a potential hydrogen-based energy landscape. The collaboration between Washington and Lee University and Texas A&M University, with contributions from doctoral student Lai Jiang, marks a significant step towards unraveling the mysteries of metal failures in hydrogen-rich environments.