Spain is poised to lead Europe's clean industrial revolution by utilizing innovative financing, public-private partnerships, and regional collaboration to develop cleantech industrial clusters. The country has set ambitious targets to generate 81% of its energy from renewable sources by 2030. Despite progress driven by the public sector, Spain faces challenges in financing cleantech projects, including high capital requirements, market uncertainty, technological risk, and regulatory complexities. Industrial clusters are seen as a solution to facilitate scalability, optimize resource allocation, and encourage innovative funding strategies. Spain's experience in scaling industrial clusters offers valuable lessons for other regions, with initiatives like the Basque industrial 'super cluster' and the Andalusian Green Hydrogen Valley showcasing the country's potential. The article highlights the importance of balanced economic, social, and environmental value in transitioning industrial clusters and emphasizes cross-sectoral collaboration. To unlock Spain's cleantech potential, decisive action is needed across various fronts, such as promoting demand signals, streamlining financing mechanisms, and channeling Emission Trading System revenues into cleantech innovation.