A recent report commissioned by E.ON and Thüga Group, conducted by the Institute of Energy Economics at the University of Cologne (EWI), highlights the significant role that electrolyzers can play in optimizing Germany's energy system. The report identifies various regions in Germany suitable for the construction of electrolyzers, emphasizing their potential to meet the demand for hydrogen and enhance system flexibility. By 2030 and particularly by 2040, the placement of electrolyzers in key regions like Dithmarschen, the central German chemical triangle, northern Germany, the Ruhr area, and the Rhineland can greatly benefit the energy transition. The report underscores that electrolyzers can alleviate pressure on electricity grids, prevent curtailments, and support the expansion of hydrogen networks. It also stresses the importance of utilizing regionally generated renewable electricity for electrolysis to enhance system flexibility and reduce system costs. The findings suggest that a system-friendly approach to electrolyzer placement can contribute to decarbonization efforts, improve security of supply, and promote regional value creation. Gabriël Clemens of E.ON Hydrogen highlights the significance of electrolyzers in linking sectors and providing flexibility in the energy system. Christoph Ullmer from Thüga AG emphasizes the need to use green molecules for decarbonization and stresses that the system-friendly use of electrolyzers can reduce economic costs, enhance security of supply, and support regional development. The report's site assessment criteria include factors such as regional renewable energy potential, grid infrastructure, hydrogen transportation, storage facilities, demand, and land availability. The weighted assessment of these criteria provides insights to guide the optimal placement of electrolyzers. Overall, the report advocates for a strategic approach to electrolyzer deployment to maximize the benefits for Germany's energy transition.