In a recent study published in Angewandte Chemie International Edition, researchers from the Fujian Institute of Research on the Structure of Matter of the Chinese Academy of Sciences developed an innovative acid/alkali asymmetric electrolyzer for the simultaneous production of formic acid from CO2 reduction and methanol electrooxidation. By coupling the cathodic acidic-CO2 reduction with anodic alkali-methanol electrooxidation, the researchers achieved high efficiency and stability in formic acid production. The electrolyzer, utilizing Cu2Se@CuO nanoflowers and Bi/BiOx nanosheets as catalysts for the cathode and anode, operated stably for more than 90 hours. It demonstrated a total Faraday efficiency exceeding 190% and required only 2.1 V to achieve a formic acid partial current density of approximately 130 mA cm-2. This efficiency was achieved while consuming three times less electricity compared to conventional CO2RR-OER systems. The success of the acid/alkali hybrid electrolyzer can be attributed to the integration of high-performance catalysts, the pairing with methanol electrooxidation, and the effective utilization of electrochemical neutralization energy. The study not only presents a pathway for efficient CO2 electrolysis but also underscores the development of advanced electrocatalysts for sustainable and energy-efficient production of valuable chemicals. Led by Prof. Wen Zhenhai and Assoc. Prof. Chen Qingsong, the research team's work sheds light on novel techniques for electron efficiency and energy conservation in electrolysis processes.