Scientists from Spain’s Technical University of Madrid conducted a study comparing direct and indirect configurations for PV and electrolyzers in green hydrogen production. The research, based on numerical simulations, concluded that indirect systems not only produce more hydrogen but also exhibit higher resilience to module power losses. The indirect configuration involves a power stage with a maximum power point tracker and a DC-DC converter, ensuring optimal power transfer from PV to electrolyzers despite incurring losses. The study showcased that the presence of MPPT in the indirect system allows the PV module to operate at its maximum power point for all meteorological conditions, leading to increased electric power transfer and hydrogen production. Through simulations, it was found that the indirect system injects 39.4% more electric energy into the electrolyzer annually, resulting in 37.5% more hydrogen production compared to the direct system. Additionally, the indirect system displayed an efficiency of 6.9% while the direct system achieved 5%. The study also evaluated resilience to module power losses, with the indirect system proving to be more robust and efficient in maintaining hydrogen production. The findings highlight the advantages of indirect configurations in maximizing green hydrogen production and efficiency.