The article discusses the ongoing search for sustainable alternatives to fossil fuels due to their environmental impact and geopolitical challenges. Synthetic fuels, produced by capturing CO2 from the air and combining it with clean energy, are presented as a potential solution to reduce carbon emissions in the transport sector. These synthetic fuels, known as synfuels, can be used as drop-in replacements for conventional gasoline, diesel, and jet fuel, offering a pathway to decarbonize transportation without requiring significant infrastructure changes. One of the proposed methods to produce synfuels efficiently and sustainably is through nuclear-powered processes. U.S. Department of Energy labs and the UK Nuclear Industry Association are actively involved in researching nuclear synfuel production, aiming to leverage nuclear energy to power the chemical processes involved. By utilizing nuclear reactors, both electricity and direct heat can be generated to facilitate the production of synfuels, addressing the energy-intensive nature of the synthesis process. Despite the potential benefits of nuclear synfuels, challenges such as cost competitiveness and efficiency need to be addressed to ensure widespread adoption. The article highlights the importance of achieving price parity with fossil fuels and enhancing the efficiency of synfuel production to make them financially viable alternatives. While there is optimism that nuclear-produced synfuels could reach competitive prices, further engineering and development are required. The article also discusses the role of nuclear synfuels in various sectors, particularly in applications like trucking and aviation where electrification may be challenging due to battery limitations. While nuclear synfuels show promise in reducing emissions and offering a greener fuel option, public perception of nuclear technologies could influence their acceptance and implementation in the future. In conclusion, the discussion around nuclear-powered synthetic fuels presents a potential pathway towards a more sustainable energy future. By addressing technical, economic, and social challenges, nuclear synfuels could play a crucial role in decarbonizing the transport sector and reducing reliance on fossil fuels.