The ECLIF3 study conducted in Berlin, Germany, marks a significant milestone in sustainable aviation practices. In this groundbreaking research, Airbus, Rolls-Royce, DLR, and SAF producer Neste collaborated to investigate the impact of using 100% Sustainable Aviation Fuel (SAF) on an Airbus A350 powered by Rolls-Royce Trent XWB engines. The study revealed a substantial reduction in soot particle emissions and the formation of contrail ice crystals when compared to traditional Jet A-1 fuel. Global climate model simulations conducted by DLR estimated a 26% decrease in the climate impact of contrails with the utilization of 100% SAF. This reduction has the potential to positively influence the overall environmental footprint of aviation operations. The research findings, published in the Copernicus journal Atmospheric Chemistry & Physics, provide valuable insights into the effectiveness of SAF in mitigating climate-warming effects. Key stakeholders, including Markus Fischer from DLR, Mark Bentall from Airbus, Alexander Kueper from Neste, and Alan Newby from Rolls-Royce, expressed optimism regarding the results. They emphasized the importance of SAF in reducing the aviation sector's carbon footprint and highlighted the role of sustainable aviation fuels in achieving climate-compatible aviation. The study's scientific rigor and peer-reviewed publication add credibility to the findings, indicating the potential of 100% SAF to significantly impact the reduction of contrail ice crystals and other non-CO2 effects. The ECLIF3 program's comprehensive approach, involving in-flight measurements and global simulations, sets a precedent for future research in the field of sustainable aviation and environmental impact mitigation.