The EU Energy Projects Podcast focuses on the role of Sustainable Aviation Fuel (SAF) in reducing European aviation emissions, particularly through the TAKE-OFF project supported by the EU's Horizon 2020 program. The discussion delves into the differences between aviation biofuels and power-to-liquid fuels, emphasizing the importance of efficient processes and sources for SAF production. Challenges in scaling SAF production, such as feedstock limitations and costs, are highlighted alongside the crucial role of government policies and international regulations. The conversation stresses the necessity of industry alignment and investments to enhance cost competitiveness. The episode underlines the economic implications for airlines and consumers, emphasizing the need for technological advancements and policy support to achieve net-zero aviation emissions by 2050.