The Dutch Innovation Company (NIM) has embarked on the groundbreaking H2ESTIA Project, with the goal of creating the world's first zero-emission general cargo ship powered by liquid hydrogen. This initiative, supported by the Dutch Ministry of Infrastructure and Water Management, plays a vital role in the Maritime Masterplan to decarbonize European maritime logistics. The project encompasses designing, constructing, and demonstrating a hydrogen-powered cargo vessel for operations in the North Sea and beyond, managed by Van Dam Shipping. Key features include an integrated hydrogen propulsion system, cryogenic hydrogen storage, and a bunkering system for safe liquid hydrogen handling. The vessel will utilize a hydrogen fuel cell system, combined with batteries, for primary propulsion, alongside energy efficiency solutions like wind-assisted propulsion and waste heat recovery. Digital twin technology will enable real-time monitoring and operational optimization. NIM's CTO highlighted the project's significance for commercial shipping, showcasing the feasibility of zero-emission shipping. The project aims to prove technological readiness and economic viability while addressing challenges like hydrogen system certification and crew training. Collaboration among industry leaders like TNO, MARIN, and the University of Twente enhances the project's success, emphasizing the importance of joint efforts in realizing ambitious sustainability goals.