Clean hydrogen is gaining attention as a key player in decarbonization efforts, especially in challenging sectors like industry and heavy transport. The Infrastructure Investment and Jobs Act allocated $7 billion to the Department of Energy for the Regional Clean Hydrogen Hubs program, aiming to establish seven hubs across the United States. These hubs will serve as crucial centers for integrating hydrogen into different parts of the economy. They will encompass a mix of energy sources, hydrogen production methods like electrolytic hydrogen and biohydrogen, transport infrastructure, and end-use applications tailored to local needs. The Great Plains Institute (GPI) partnered with Rhodium Group to analyze the economic advantages associated with four selected hydrogen hubs. These hubs were chosen for their diverse locations and the range of hydrogen production pathways they represent, such as SMR with carbon capture. The findings of this analysis shed light on the significant economic benefits that can arise from investing in clean hydrogen infrastructure and technology.