Trucks and buses play a crucial role in the diverse landscape of heavy-duty road transport in Europe. Not just larger versions of cars, these vehicles serve a wide range of purposes tailored to specific needs such as logistics and public transport. They are instrumental in constructing and maintaining the green infrastructure of Europe, supporting decarbonisation efforts across various sectors. Industry stakeholders have set ambitious targets to go fossil-free by 2040 and achieve climate neutrality by 2050. To meet these goals, manufacturers are heavily investing in battery-electric and hydrogen-powered vehicles. However, the success of these initiatives relies heavily on the presence of suitable enabling conditions. Without stable planning and supportive measures, transport operators are unlikely to adopt new vehicle technologies. Policymakers play a crucial role in implementing frameworks that match the manufacturers' goals, promoting the uptake of zero-emission vehicles. An upcoming Euractiv event will delve into the primary challenges facing truck manufacturers in meeting the market demand for zero-emission vehicles, the essential conditions needed for rapid market uptake, and the progress made in infrastructure development including charging stations and hydrogen refuelling facilities. This event aims to pave the way forward in decarbonising heavy-duty road transport and fostering a sustainable transport industry.