Sustainability goals have become a critical aspect of corporate strategy, leading to a reevaluation of industrial site selection priorities. Industrial decarbonization has emerged as a key consideration for manufacturers, significantly impacting site selection decisions. The U.S. government's focus on directing capital towards decarbonizing hard-to-abate sectors is driving the industrial energy transition. Notable investments and attention in clean technologies are influencing site selection, with a shift towards decarbonization options. Various trends such as utilizing end-of-life material feedstock, low-carbon fuels like hydrogen, carbon capture and sequestration, and renewable electricity are shaping site selection strategies. The decline in decarbonization technology costs and the stabilization of industry standards around green technologies like hydrogen present opportunities for corporate executives and economic development practitioners. Adaptation to decarbonization trends and readiness for industrial energy transitions are highlighted as crucial for attracting manufacturing capital investment and job creation in the future.