Sustainability goals have significantly influenced corporate strategies, prompting industrial manufacturers to reconsider their site selection criteria. Decarbonization has emerged as a crucial factor in this process, reshaping how companies approach location decisions. The industrial sector, responsible for 1.41 billion metric tons of carbon emissions annually, is undergoing a substantial energy transition. Various legislative initiatives and significant capital investments are driving the adoption of decarbonization technologies. The surge in attention and funding has notably impacted site selection, with decarbonization options becoming a critical consideration for heavy industries. Key trends include the use of end-of-life materials, the emergence of low-carbon fuels like blue and green hydrogen, carbon capture and sequestration, and the demand for renewable electricity. The decreasing costs of decarbonization technologies and the stabilization of industry standards around green hydrogen and electrolysis are expected in the long run. This transition presents opportunities for cost optimization and flexibility in decarbonization pathways for corporate executives. Communities that proactively prepare sites for decarbonization will be better positioned to attract manufacturing investments and job creation in the future.