Worldwide, efforts to decarbonize 'hard-to-abate' sectors like shipping and chemical manufacturing are intensifying. E-methanol, derived from green hydrogen and captured CO2, emerges as a promising solution due to its closed carbon cycle and versatility as a sustainable fuel and feedstock. The International Maritime Organization (IMO) aims to reduce shipping emissions by 20% by 2030, creating a demand for cleaner fuels like e-methanol. E-methanol production involves green hydrogen generation, CO2 capture, and methanol synthesis, resulting in a fuel with low emissions and even carbon negativity. The shipping industry shows increasing interest in methanol-fueled vessels, with companies like Maersk ordering ships expected to significantly cut CO2 emissions. Similarly, in chemical manufacturing, e-methanol can decarbonize supply chains without altering processes. Despite being more costly than traditional methanol, advancements in production methods and policies like carbon pricing could drive down costs and accelerate adoption. Modular e-methanol plants, supported by initiatives like UP-TO-ME, offer a more flexible and cost-effective approach. To achieve mainstream adoption, supportive policies such as lifecycle emissions standards and carbon pricing mechanisms are essential. E-methanol's potential to reduce emissions in challenging sectors makes it a key player in the transition towards a cleaner, sustainable future.