The push for greener transportation is driving operators to consider sustainable fuel options for commercial vehicles. While electric powertrains are in the spotlight, challenges such as infrastructure and cost hinder widespread adoption. Alternative fuels like natural gas (CNG/LNG) provide extended travel ranges, cleaner combustion, and lower costs. Biofuels such as biodiesel and renewable diesel offer drop-in solutions compatible with existing diesel engines, reducing emissions significantly. Hydrogen fuel technology, including fuel cells and internal combustion engines, shows promise for high efficiency and reduced refuelling times. However, robust infrastructure and safety measures are essential due to hydrogen's flammability. Fleet and driver management practices are crucial for optimizing efficiency, uptime, and total cost of ownership (TCO). Telematics systems, driver training on eco-driving, and preventive maintenance play key roles in enhancing operational efficiency. Collaboration with suppliers to ensure fuel quality and developing adequate refuelling and maintenance infrastructure are vital for the successful deployment of alternative fuel vehicles. Despite the challenges, the advancements in sustainable fuels provide a promising outlook for the future of commercial transportation.