The United States Department of Energy (DOE) has announced a groundbreaking $2.2bn investment in two Regional Clean Hydrogen Hubs— the Gulf Coast H2Hub in Texas and the Midwest H2Hub covering Illinois, Indiana, Iowa, and Michigan. These hubs are designed to accelerate the deployment of clean hydrogen at a commercial scale, bringing about substantial economic and environmental benefits. Clean hydrogen is highlighted as a game-changer for energy and emissions reduction in high-impact industries. The versatile energy carrier, produced using various methods including renewable resources and fossil fuels with carbon capture, offers near-zero emissions potential. By incorporating hydrogen into heavy-duty transportation, chemical manufacturing, and energy storage, the DOE initiative aims to decarbonize energy-intensive sectors and promote US energy independence. Both the Gulf Coast and Midwest Hydrogen Hubs are envisioned to create tens of thousands of direct jobs and significantly contribute to industrial decarbonization in their regions. These hubs are part of the DOE's larger plan to establish a network of clean hydrogen hubs across the country, supporting the nation's 2030 production targets and playing a crucial role in reducing CO2 emissions to combat climate change. Overall, the DOE's investment seeks to drive private sector involvement, amplify economic impacts, and position the US as a key player in the global clean hydrogen economy.