China's Guangdong Province, specifically the cities of Shenzhen and Foshan, has emerged as a leader in zero-emission truck adoption, with over 28,000 sales in 2023 driven by government policies. This progress showcases the importance of transitioning to zero-emission trucks to mitigate air pollution, protect public health, and reduce emissions. However, the shift towards zero-emission trucks faces challenges relating to high upfront costs, operational limitations, and the dominance of small and midsized trucking businesses that lack capital. The EU and California have set ambitious targets for reducing carbon emissions from heavy-duty vehicles, emphasizing the global need for sustainable transportation solutions. Lessons from Guangdong's success include the importance of identifying cost-effective use cases to accelerate adoption, addressing energy prices to maintain cost competitiveness, and implementing strategies like choosing smaller battery packs and optimizing charging schedules to reduce total cost of ownership. These efforts are crucial for promoting the widespread adoption of zero-emission trucks and achieving a more sustainable future in the transportation sector.